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Monday, March 24, 2008


Drug: Hyoscine butylbromide

Use: Smooth muscle anti-spasmodic

Buscopan is an antimuscarinic medicine that is indicated for the symptomatic relief of gastro-intestinal spasms (stomach and bowel cramps) associated with irritable bowel syndrome. It works by exerting an antispasmodic effect on the smooth muscle of the bowel.

It may also be given to relieve genetio-urinary muscle spasms.


Typical dose is 10mg 3 times daily.

Adult dose may be increased if required up to to 20mg 4 times daily (max 80mg/day).


- oesophageal reflux
- diarrhoea
- ulcerative colitis
- high blood pressure
- fever
- pregnancy and breastfeeding (safety not yet been established).


- glaucoma
- myasthenia gravis
- paralytic ileus
- pyloric stenosis
- prostatic enlargement
- porphyria

Side effects:

Side effects include constipation, dry mouth, photophobia, flushing, skin rash. Busopan may also cause urinary urgency and urinary retention.

Less common side effects include confusion, nausea, vomiting and dizziness.


No known interactions following oral dose.

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