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Monday, March 24, 2008


Bowel anti-inflammatories include mesalazine, olsalazine and sulphasalazine. They belong to a group of drugs called aminosalicylates and are use to control bowel inflammation.


Aminosalicylates are used to treat inflammatory bowel disease (ulcerative colitis and Crohn's disease) and to maintain remission.

They work by acting locally in the bowel, exhibiting an anti-inflammatory and immunosuppressive effect on the gut wall.


Gastrointestinal side-effects are common (nausea, vomiting, diarrhoea).

Less common side effects include headache, exacerbation of the colitis, and hypersensitivity reactions.

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